Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.
Gary OldmanDr. Tyrone Brower
Armie HammerJake Kelly
Evangeline LillyClaire Reimann
Greg KinnearDean Talbot
Michelle RodriguezSupervisor Garrett
Luke EvansDr. Bill Simons
Lily-Rose DeppEmmie Kelly
Guy NadonMother
Veronica FerresDr. Meg Holmes
Kid CudiBen Walker
Mia KirshnerSusan
Michael AronovMinas
